Annals of hematology
-
Annals of hematology · May 2007
Clinical TrialZinc protoporphyrin, a useful parameter to address hyperferritinemia.
Zinc protoporphyrin (ZPP) is produced instead of heme as soon as iron support to erythropoiesis becomes insufficient. In iron deficiency the intra-erythrocytic ZPP concentration is increased. The aim of this study was to investigate whether ZPP is influenced by increased iron levels in hereditary hemochromatosis (HE) and is useful in the clarification of hyperferritinemia. ⋯ In contrast to HE, ZPP values