Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
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Cancer Epidemiol. Biomarkers Prev. · Feb 2016
Breast Cancer Risk Prediction Using Clinical Models and 77 Independent Risk-Associated SNPs for Women Aged Under 50 Years: Australian Breast Cancer Family Registry.
The extent to which clinical breast cancer risk prediction models can be improved by including information on known susceptibility SNPs is not known. ⋯ Our estimates of the increased performance of clinical risk prediction models from including genetic information could be used to inform targeted screening and prevention.