Pharmacoepidemiology and drug safety
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Pharmacoepidemiol Drug Saf · Nov 2014
ReviewMortality rate in so-called "metformin-associated lactic acidosis": a review of the data since the 1960s.
The aim of this study is to study the mortality rate in so-called "metformin-associated lactic acidosis" (MALA) from the 1960s to date and to establish whether the rate has changed over time. ⋯ The overall mortality rate for MALA was around 50% during the period 1960-2000 but has since fallen to around 25%.