Neuroimaging clinics of North America
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Neuroimaging Clin. N. Am. · Nov 2005
ReviewThe role of quantitative structural imaging in the early diagnosis of Alzheimer's disease.
The goal of this article is to review the role of structural neuroimaging in the diagnosis of Alzheimer's disease (AD). We present relevant neuroanatomy, highlight progress in the domain of AD imaging, and review the clinical characteristics of the prodromal phase of AD. ⋯ The article delineates the differences between subjects who have mild cognitive impairment and AD, which illustrate the spreading of the pathology with disease progression. The last section describes problems encountered in the differential diagnosis.