Neuroimaging clinics of North America
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Neuroimaging Clin. N. Am. · May 2012
ReviewDiffusion tensor and perfusion imaging of brain tumors in high-field MR imaging.
Diffusion tensor imaging (DTI) and perfusion-weighted imaging (PWI) are essential tools for diagnosing, differentiating, and monitoring brain tumors. High-field MRI provides higher signal-to-noise ratio, shorter scan time, and better image quality. ⋯ PWI provides reliable biomarkers for glioma grading, therapeutic responses, and differential diagnosis of various brain tumors. With higher field strength, better-quality DTI and PWI can raise the diagnostic accuracy in brain tumors.
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High-field magnetic resonance (MR) imaging is showing potential for imaging of neurodegenerative diseases. 7 T MR imaging is beginning to be used in a clinical research setting and the theoretical benefits of higher signal-to-noise ratio, sensitivity to iron, improved MR angiography, and increased spectral resolution in spectroscopy are being confirmed. Despite the limited number of studies to date, initial results in patients with multiple sclerosis, Alzheimer disease, and Huntington disease show promising additional features in contrast that may help the diagnosis of these disorders.
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Neuroimaging Clin. N. Am. · May 2012
ReviewCurrent state-of-the-art 1.5 T and 3 T extracranial carotid contrast-enhanced magnetic resonance angiography.
Recent advances in magnetic resonance (MR) hardware and software have improved the resolution and spatial coverage of head and neck first-pass contrast-enhanced (CE) MR angiography. Despite these improvements, high-quality submillimeter-resolution 1.5 T and 3 T carotid CE MR angiography is not consistently available in the general radiology practice. This article reviews the important imaging parameters and potential pitfalls that affect carotid CE MR angiography image quality, and the dose and timing of the gadolinium-based contrast agent, and summarizes vendor-specific protocols for high-quality submillimeter-resolution carotid CE MR angiography at 1.5 and 3 T.
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High-field 3 T magnetic resonance (MR) imaging provides greater signal-to-noise ratio (SNR) compared with 1.5 T systems. Various MR imaging clinical applications in children can benefit from improvements resulting from this increased SNR. ⋯ However, challenges inherent to 3 T imaging become more relevant in children. The use of 3 T imaging in children has allowed better diagnostic efficacy in neuroimaging, but certain technique modifications may be required for optimal imaging.
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Neuroimaging Clin. N. Am. · May 2012
ReviewUltrahigh-field magnetic resonance imaging: the clinical potential for anatomy, pathogenesis, diagnosis, and treatment planning in brain disease.
In this review, current (clinical) applications and possible future directions of ultrahigh-field (≥7 T) magnetic resonance (MR) imaging in the brain are discussed. Ultrahigh-field MR imaging can provide contrast-rich images of diverse pathologies and can be used for early diagnosis and treatment monitoring of brain disease. ⋯ Several limitations need to be overcome before worldwide clinical implementation can be commenced. Current literature regarding clinically based ultrahigh-field MR imaging is reviewed, and limitations and promises of this technique are discussed, as well as some practical considerations for the implementation in clinical practice.