Transfusion medicine
-
Transfusion medicine · Dec 2020
Clinical Trial Observational StudySurvey to assess knowledge, attitude and practices for safe and efficient vein-to-vein transfusion practices and effect of educational intervention in a hospital setting.
The primary aim was to assess the knowledge, attitude and practices (KAP) of employees (medical, paramedical and other hospital staff) towards blood donation and transfusion practices in a tertiary care hospital. A secondary objective was to assess and interpret the effect of an educational module on improvement in the KAP of employees in a hospital setting. ⋯ Educational intervention is an important tool for improving KAP among not only physicians but hospital staff as well.
-
Transfusion medicine · Aug 2019
Multicenter Study Clinical TrialSafety and effectiveness of a prothrombin complex concentrate in approved and off-label indications.
To evaluate the effectiveness and safety of prothrombin complex concentrates (PCCs) in approved and off-label indications. ⋯ 4F-PCC was effective as adjuvant treatment with an acceptable safety profile, not only for the emergent reversal of VKAs but also for refractory coagulopathy associated with major bleeding.
-
Transfusion medicine · Jun 2019
Randomized Controlled Trial Multicenter StudyCaplacizumab treatment for acquired thrombotic thrombocytopenic purpura (HERCULES trial).
In people with acquired thrombotic thrombocytopenic purpura (TTP), does caplacizumab decrease the time to normalisation of the platelet count and the risk of death and complications caused by thrombotic events and organ damage? ⋯ In adults with acquired TTP, caplacizumab decreased the time to normalisation of the platelet count and decreased the risk of TTP-related death and recurrence of TTP.
-
Transfusion medicine · Apr 2019
Multicenter StudyCost-effectiveness of alternative changes to a national blood collection service.
To evaluate the cost-effectiveness of changing opening times, introducing a donor health report and reducing the minimum inter-donation interval for donors attending static centres. ⋯ The introduction of a donor health report is unlikely to provide a sufficient increase in donation frequency to justify the additional costs. A more cost-effective change is to extend opening hours for blood collection at static centres.