Osteoarthritis and cartilage
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Osteoarthr. Cartil. · Oct 2012
Prevalence of symptomatic lumbar spinal stenosis and its association with physical performance in a population-based cohort in Japan: the Wakayama Spine Study.
The purpose of this study was to investigate the prevalence of symptomatic lumbar spinal stenosis (LSS) and to clarify the association between symptomatic LSS and physical performance using magnetic resonance imaging (MRI) in a population-based cohort. ⋯ The prevalence of symptomatic LSS was approximately 10% in a cohort resembling the general Japanese population. A 6-m walking time at a maximal pace was a more sensitive index than walking at a usual pace in assessing decreased physical performance associated with symptomatic LSS.
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Osteoarthr. Cartil. · Oct 2012
Associations between pre-operative radiographic changes and outcomes after total knee joint replacement for osteoarthritis.
To assess the influence of pre-operative X-ray changes on the response to total knee joint replacement (TKR). ⋯ Patients with more severe radiographic knee damage at the time of surgery are most likely to have substantial gains in terms of both pain relief and improved function as a result of a TKR.
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Osteoarthr. Cartil. · Sep 2012
Association between spinal morning stiffness and lumbar disc degeneration: the Rotterdam Study.
To explore the associations between spinal morning stiffness and lumbar disc degeneration (LDD). ⋯ Reported spinal morning stiffness is associated with LDD. The associations increased when we combined spinal morning stiffness with low back pain. The magnitude of the association for the definition 'narrowing' is similar to the association between morning stiffness in the legs and knee or hip OA.
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Osteoarthr. Cartil. · Aug 2012
Comparative StudyConsequences of handling missing data for treatment response in osteoarthritis: a simulation study.
To understand how handling of missing data influences the statistical power and bias of treatment effects in randomised controlled trials of painful knee osteoarthritis (OA). ⋯ Multiple imputation of missing data may be used to decrease bias/MSE and increase power in OA trials. These results can guide investigators in the choice of outcome measures and especially how missing data can be handled.