Physiological measurement
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Physiological measurement · Dec 2015
Permutation Lempel-Ziv complexity measure of electroencephalogram in GABAergic anaesthetics.
Monitoring the brain state in anaesthesia is crucial for clinical doctors. In this study, we propose a novel nonlinear method, the permutation Lempel-Ziv complexity (PLZC) index, which describes the complexity in the electroencephalographic (EEG) signal to quantify the effect of GABAergic anaesthetics on brain activities. We applied the PLZC to two EEG data sets that were recorded under sevoflurane and propofol anaesthesia. ⋯ PLZC based on electroencephalogram signals can be used as a new index to characterize the depth of anaesthesia. This index outperformed LZC, PE, CPEI, RE, SE, and BIS or SFS in tracking drug concentration changes during GABAergic anaesthetics. PLZC is a potentially superior method for applications in intra-operative monitoring.