The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
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Am J Geriatr Psychiatry · Jun 2005
Serum anticholinergic activity and cognition in patients with moderate-to-severe dementia.
The authors investigated the association between serum anticholinergic activity (SAA) and cognitive performance in a group of patients with moderate-to-severe dementia. ⋯ This study extends to patients with moderate-to-severe dementia the finding that higher SAA is associated with lower cognitive performance.
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Am J Geriatr Psychiatry · Jun 2005
Neuropsychiatric symptoms and quality of life in Alzheimer disease.
Authors examined the impact of neuropsychiatric symptoms in Alzheimer disease (AD) patients' and caregivers' quality of life (QOL) and assessed the relationship of caregiver distress to neuropsychiatric symptoms and caregiver QOL. ⋯ Neuropsychiatric symptoms of AD patients adversely affect both patient and caregiver QOL. These results suggest that identifying and treating neuropsychiatric symptoms in AD may improve both patient and caregiver QOL.