Medicina
-
Infection with high-risk human papillomaviruses is a significant risk factor of various benign and malignant human lesions in the upper respiratory tract, skin and the genital tract. The identification of particular human papillomaviruses types is important for identifying patients with premalignant lesions who are at risk of progression to malignancy. Our aim was to establish the prevalence of human papillomaviruses infection in the upper respiratory tract of patients with laryngeal papillomatosis, to identify viral types, to evaluate the relationship between some risk factors and persistence of human papillomaviruses in the upper respiratory tract and to determine the pattern of human papillomaviruses infection. ⋯ The prevalence of human papillomaviruses infection in the upper respiratory tract of patients with laryngeal papillomatosis is high; human papillomaviruses 6, 11 types are predominant. High-risk human papillomaviruses were noted statistically significantly more often in the group of patients with laryngeal papillomatosis. Inclination to diseases of respiratory system, dental caries, smoking, low living standard are statistically significantly related to human papillomaviruses persistence in the upper respiratory tract.
-
Case Reports Comparative Study
[Simultaneous myocardial revascularization and abdominal aortic aneurysm repair (report of a fatal case)].
Patients with coronary disease associated with abdominal aortic aneurysm or aortoiliac occlusive disease often raise problems of operative strategy. In particular, the order in which these lesions should be treated is a frequent source of controversy. Our approach for the past two years has been a combined myocardial revascularization with abdominal aortic reconstruction in patients with both lesions. ⋯ We report here the fatal case of combined coronary artery bypass grafting and abdominal aortic aneurysm repair. Partial heparinization and operation without extracorporeal circulation caused acute thrombosis of abdominal aortic aneurysm and femoral arteries. Our first experience advocates using total heparinisation and cardiopulmonary bypass for combined cardiac-aortic procedures.
-
Comparative Study
[Knee joint evaluation after anterior cruciate ligament plasty].
To make certain how the patients themselves evaluate the state of their knee joint and check-up the state objectively after 3, 6, 12 months period after the anterior cruciate ligament reconstruction. ⋯ For all questioned patients the instability of the knee joint after the anterior cruciate ligament reconstruction disappeared; 95% patients are satisfied with the results of the operation.
-
Under the influence of strong electric fields the permeability of tumor cell membranes to poor permeating drugs increases and as a result the tumor growth is inhibited. This new tumor treatment method is named electrochemotherapy. We investigated the electrochemotherapy influence of bleomycin upon mice Lewis Lung Carcinoma by using optical histological and electron microscopic tumor analysis. ⋯ Cell and nucleus membranes break as well as hemorrhage are very often. The observable histological tumor change was noted when electrical pulses of 1300 V/cm and 0.1 ms duration were applied. Pulses of 1700 V/cm and 0.1 ms duration induce total tumor destruction.
-
Adrenogenital syndrome, or so called congenital adrenal hyperplasia, is caused by a congenital insufficiency of the enzyme 21-hydroxylase, which is responsible for converting cortisol into cholesterol. Because of virilizing effect of androgens overproduction girls develop clitoral hypertrophy and persistent urogenital sinus (common channel for urethra and vagina). Surgical treatment is recommended in order to repair those developmental faults. ⋯ Postoperatively the patients were observed for 0.5-5 years, the close results showed to be good. There were 4 cases of vaginal stenosis and 2 cases of urethrovaginal fistula (all successfully repaired later). Early one staged genitoplasty and postoperative vaginal dilatations for the period of 6-12 months is recommended.