Archives of disease in childhood. Fetal and neonatal edition
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Arch. Dis. Child. Fetal Neonatal Ed. · Sep 2011
Multicenter Study Comparative StudyNeonatal intensive care outcomes and resource utilisation of infants born <26 weeks in the former Trent region: 2001-2003 compared with 1991-1993.
To provide survival data and rates of severe disability at 2 years of corrected age in infants born prior to 26 weeks' gestation in 2001-2003 and to compare these outcomes with an earlier cohort from 1991 to 1993. ⋯ This study has shown an improvement in survival to discharge in babies admitted for neonatal care. However, this improved survival has been associated with an increase in the proportion of children with at least one severe disability at a corrected age of 2 years.
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Arch. Dis. Child. Fetal Neonatal Ed. · Sep 2011
Randomized Controlled TrialPositive effects of early continuous positive airway pressure on pulmonary function in extremely premature infants: results of a subgroup analysis of the COIN trial.
Early continuous positive airway pressure (CPAP) may reduce lung injury in preterm infants. ⋯ Early CPAP is feasible, shortens the duration of respiratory support and results in improved lung mechanics and decreased work of breathing.
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Arch. Dis. Child. Fetal Neonatal Ed. · Sep 2011
Assessment of newborn resuscitation skills of physicians with a simulator manikin.
Education of medical staff according to Neonatal Resuscitation Program guidelines improves outcome of delivery room resuscitation. Regular assessment of skills is important for reliable performance of neonatal resuscitation. We assessed the practical resuscitation skills of clinicians in a standard scenario in a newborn simulation. ⋯ Many clinicians exhibited inadequate skills to resuscitate a newborn infant in a standard scenario. The neonatologists, as clinical experts, performed best in both technical and non-technical skills testing.
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Arch. Dis. Child. Fetal Neonatal Ed. · Sep 2011
Oxygen saturation profile in healthy preterm infants.
To establish a reference range for oxygen saturation (SpO(2)) in well preterm infants to guide home oxygen therapy using a pulse oximeter and Pulse Oximetry Data Analysis Software (PODS). ⋯ The SpO(2) reference range can be used as an easy and practical guide to compare SpO(2) profiles of infants on home oxygen therapy and guide their oxygen therapy.
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Arch. Dis. Child. Fetal Neonatal Ed. · Sep 2011
Predictors of early nasal CPAP failure and effects of various intubation criteria on the rate of mechanical ventilation in preterm infants of <29 weeks gestational age.
Delivery room management using early nasal continuous positive airway pressure (nCPAP) may delay surfactant therapy. ⋯ Medical history or initial blood gas values are poor predictors of subsequent nCPAP failure. A threshold FiO(2) of ≥0.35-0.45 compared to ≥0.6 for intubation would shorten the time to surfactant delivery without a relevant increase in intubation rate. An individualised approach with a trial of early nCPAP and prompt intubation and surfactant treatment at low thresholds may be the best approach in very low birthweight infants.