Inflammation research : official journal of the European Histamine Research Society ... [et al.]
-
Severe trauma leads to an increased vulnerability to bacterial sepsis. In the present study, we compared the immunostimulating potential of granulocyte-colony stimulating-factor (G-CSF), granulocyte-macrophage colony-stimulating factor (GM-CSF) and interferon-gamma (IFN-gamma). ⋯ These data suggest that GM-CSF and IFN-gamma may serve to support immune functions in severely injured patients.