Investigative radiology
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Investigative radiology · Sep 2007
Comparative StudyFirst-pass whole-body magnetic resonance angiography (MRA) using the blood-pool contrast medium gadofosveset trisodium: comparison to gadopentetate dimeglumine.
To evaluate gadofosveset trisodium for first-pass magnetic resonance angiography (MRA) in the setting of whole-body MRA (WB-MRA). ⋯ Gadofosveset trisodium serves well for first-pass imaging in WB-MRA.
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Investigative radiology · Sep 2007
High-resolution three-dimensional aortic magnetic resonance angiography and quantitative vessel wall characterization of different atherosclerotic stages in a rabbit model.
Atherosclerosis results in a considerable medical and socioeconomic impact on society. We sought to evaluate novel magnetic resonance imaging (MRI) angiography and vessel wall sequences to visualize and quantify different morphologic stages of atherosclerosis in a Watanabe hereditary hyperlipidemic (WHHL) rabbit model. ⋯ A combination of novel 3D magnetic resonance angiography and high-resolution 3D vessel wall MRI enabled quantitative characterization of various atherosclerotic stages including positive arterial remodeling and Gd uptake in a WHHL rabbit model using a commercially available 1.5 T MRI system.
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Investigative radiology · Aug 2007
Comparative StudyBrain tumor enhancement in MR imaging at 3 Tesla: comparison of SNR and CNR gain using TSE and GRE techniques.
The purpose of this study was to compare brain and tumor signal characteristics of T1-weighted turbo spin-echo (TSE) and gradient recalled echo (GRE) sequence techniques at 3 T compared to TSE at 1.5 T, focusing on the detection of contrast enhancement, in a standardized animal model of a brain glioma. ⋯ With TSE at 3 T, the SNR gain comes close to the theoretically expected doubling with an even higher tumor CNR increase. In a clinical like setting at 3 T, where a T1w GRE sequence is used, tumor CNR gain is limited. Contrast dose should therefore not be decreased at 3 T.
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Investigative radiology · Jun 2007
Reproducibility of quantitative cerebral T2 relaxometry, diffusion tensor imaging, and 1H magnetic resonance spectroscopy at 3.0 Tesla.
The reproducibility of quantitative cerebral T2 relaxometry, diffusion tensor imaging, and H magnetic resonance (MR) spectroscopic imaging was assessed on a clinical 3.0 T MR system. ⋯ The reproducibility of quantitative brain MRI at 3.0 T is better than or at least comparable to the reproducibility at 1.5 T.
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To explore the feasibility of 3T magnetic resonance (MR) diffusion tensor imaging (DTI) and fiber tracking (FT) in patients with prostate cancer. ⋯ Three Tesla DTI of the prostate gland is feasible and has the potential for providing improved diagnostic information.