Annals of internal medicine
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The relationship between coffee consumption and mortality in diverse European populations with variable coffee preparation methods is unclear. ⋯ European Commission Directorate-General for Health and Consumers and International Agency for Research on Cancer.
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Review Meta Analysis
Treatment of Latent Tuberculosis Infection: An Updated Network Meta-analysis.
Treatment of latent tuberculosis infection (LTBI) is an important component of tuberculosis (TB) control, and this study updates a previous network meta-analysis of the best LTBI treatment options to inform public health action and programmatic management of LTBI. ⋯ U.K. National Institute for Health Research. (PROSPERO: CRD42016037871).
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Review
Cardiovascular Disease Among Transgender Adults Receiving Hormone Therapy: A Narrative Review.
Recent reports estimate that 0.6% of adults in the United States, or approximately 1.4 million persons, identify as transgender. Despite gains in rights and media attention, the reality is that transgender persons experience health disparities, and a dearth of research and evidence-based guidelines remains regarding their specific health needs. The lack of research to characterize cardiovascular disease (CVD) and CVD risk factors in transgender populations receiving cross-sex hormone therapy (CSHT) limits appropriate primary and specialty care. ⋯ For transgender women, CSHT has known thromboembolic risk, and lower-dose transdermal estrogen formulations are preferred over high-dose oral formulations. In addition, many studies of transgender adults focus predominantly on younger persons, limiting the generalizability of CSHT in older transgender adults. The lack of randomized controlled trials comparing various routes and formulations of CSHT, as well as the paucity of prospective cohort studies, limits knowledge of any associations between CSHT and CVD.