Annals of internal medicine
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Comment Randomized Controlled Trial
In primary care, second-line IBS therapy with amitriptyline vs. placebo reduced symptoms at 6 mo.
Ford AC, Wright-Hughes A, Alderson SL, et al; ATLANTIS trialists. Amitriptyline at low-dose and titrated for irritable bowel syndrome as second-line treatment in primary care (ATLANTIS): a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet. 2023;402:1773-1785. 37858323.
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Comment Randomized Controlled Trial
In women aged 45 to 75 y, opt-out vs. opt-in breast cancer screening outreach did not increase mammography rates.
Marcotte LM, Deeds S, Wheat C, et al. Automated opt-out vs opt-in patient outreach strategies for breast cancer screening: a randomized clinical trial. JAMA Intern Med. 2023;183:1187-1194. 37695621.
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Days spent obtaining health care outside the home can represent not only access to needed care but also substantial time, effort, and cost, especially for older adults and their care partners. Yet, these "health care contact days" have not been characterized. ⋯ National Institute on Aging.