Annals of internal medicine
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Review Meta Analysis
Anticoagulation Among Patients Hospitalized for COVID-19 : A Systematic Review and Prospective Meta-analysis.
Reported results of clinical trials assessing higher-dose anticoagulation in patients hospitalized for COVID-19 have been inconsistent. ⋯ No direct funding. (PROSPERO: CRD42020213461).
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Review Meta Analysis
Effect of Weight Loss Interventions on the Symptomatic Burden and Biomarkers of Polycystic Ovary Syndrome : A Systematic Review of Randomized Controlled Trials.
Polycystic ovary syndrome (PCOS) is common in women of reproductive age and is associated with obesity. Clinical guidelines recommend weight loss, but the impact on the clinical manifestations of PCOS is unclear. ⋯ National Institute for Health and Care Research School for Primary Care Research. (PROSPERO: CRD42022367488).
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Meta Analysis
In hospitalized patients with influenza, oseltamivir or peramivir may reduce hospital length of stay (low-certainty evidence).
Gao Y, Guyatt G, Uyeki TM, et al. Antivirals for treatment of severe influenza: a systematic review and network meta-analysis of randomised controlled trials. Lancet. 2024;404:753-763. 39181595.
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Review Meta Analysis
Artificial Intelligence-Assisted Colonoscopy for Polyp Detection : A Systematic Review and Meta-analysis.
Randomized clinical trials (RCTs) of computer-aided detection (CADe) system-enhanced colonoscopy compared with conventional colonoscopy suggest increased adenoma detection rate (ADR) and decreased adenoma miss rate (AMR), but the effect on detection of advanced colorectal neoplasia (ACN) is unclear. ⋯ None. (PROSPERO: CRD42023422835).
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Meta Analysis
After PCI for ACS or stable CAD, DAPT for 1 mo vs. >1 mo reduces major bleeding without increasing stent thrombosis.
Bajraktari G, Bytyçi I, Abdyli G, et al. One-month dual antiplatelet therapy reduces major bleeding compared with longer-term treatment without excess stent thrombosis: a systematic review and meta-analysis of randomized clinical trials. Am J Cardiol. 2024;227:91-97. 39029722.