Annals of internal medicine
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Hemochromatosis is an inheritable condition that mainly affects White populations of European descent. Most patients remain asymptomatic, but others develop advanced organ damage that reduces quality of life and long-term survival. ⋯ Primary care and hospital medicine physicians play an essential role in early identification of this disease, which can be accomplished via standard hematologic testing. Early diagnosis and therapeutic phlebotomy improve clinical outcomes.
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In several settings, therapeutic-dose non-vitamin K oral anticoagulants (NOACs) are superior to aspirin for the prevention of arterial and venous thromboembolism. ⋯ None. (PROSPERO: CRD42024553683).
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Various treatments for preventing episodic migraine are available. ⋯ American College of Physicians. (PROSPERO: CRD42023414305).
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Tissue-based genomic classifiers (GCs) have been developed to improve prostate cancer (PCa) risk assessment and treatment recommendations. ⋯ U.S. Department of Veterans Affairs. (PROSPERO: CRD42022347950).