Annals of internal medicine
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Randomized Controlled Trial Multicenter Study
In T1D, weekly efsitora was noninferior to daily degludec for reducing HbA1c but increased severe hypoglycemia at 26 wk.
Endocrinology: [Formula: see text].
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Randomized Controlled Trial
In HFpEF, semaglutide reduced a composite of worsening HF or CV death.
GIM/FP/GP: [Formula: see text] Cardiology: [Formula: see text].
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Randomized Controlled Trial
In HF with mildly reduced or preserved ejection fraction, finerenone reduced worsening HF or CV death at 32 mo.
GIM/FP/GP: [Formula: see text] Cardiology: [Formula: see text].
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Randomized Controlled Trial Multicenter Study
In acute ischemic stroke and a large infarct, adding EVT to medical treatment improved functional outcome at 12 mo.
Thomalla G, Fiehler J, Subtil F, et al; TENSION Investigators. Endovascular thrombectomy for acute ischaemic stroke with established large infarct (TENSION): 12-month outcomes of a multicentre, open-label, randomised trial. Lancet Neurol. 2024;23:883-892. 39074480.
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Randomized Controlled Trial
The Effect of the "Safety in Dementia" Online Tool to Assist Decision Making for Caregivers of Persons With Dementia and Access to Firearms : A Randomized Trial.
Caregivers face challenges (including competing desires to prevent injury, respect autonomy, and avoid conflict) when addressing firearm access by community-dwelling persons with Alzheimer disease and related dementias (ADRD). ⋯ National Institute on Aging, National Institutes of Health.