Annals of internal medicine
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Randomized Controlled Trial Multicenter Study
Diabetes Risk Factors in People With HIV Receiving Pitavastatin Versus Placebo for Cardiovascular Disease Prevention : A Randomized Trial.
REPRIEVE (Randomized Trial to Prevent Vascular Events in HIV) led to new guidelines for statin use among people with HIV (PWH) with low to moderate risk for atherosclerotic cardiovascular disease (ASCVD). Little is known about the natural history of diabetes mellitus (DM) or mechanisms contributing to statin effects on DM among this population. ⋯ National Heart, Lung, and Blood Institute of the National Institutes of Health.
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Randomized Controlled Trial Multicenter Study
Effectiveness of Integrating Suicide Care in Primary Care : Secondary Analysis of a Stepped-Wedge, Cluster Randomized Implementation Trial.
Primary care encounters are common among patients at risk for suicide. ⋯ National Institute of Mental Health.
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Randomized Controlled Trial
In older adults receiving high-risk medications, a deprescribing intervention did not reduce falls at 18 mo.
Phelan EA, Williamson BD, Balderson BH, et al. Reducing central nervous system-active medications to prevent falls and injuries among older adults: a cluster randomized clinical trial. JAMA Netw Open. 2024;7:e2424234. 39052289.
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Randomized Controlled Trial Multicenter Study
Long-Term Effects of Individualized Acupuncture for Chronic Neck Pain : A Randomized Controlled Trial.
Long-term effects of individualized acupuncture in persons with chronic neck pain (CNP) remain unknown. ⋯ National Natural Science Foundation of China.
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Randomized Controlled Trial
In adults with hypertension and high CV risk, intensive vs. standard BP-lowering therapy reduced major vascular events.
Liu J, Li Y, Ge J, et al; ESPRIT Collaborative Group. Lowering systolic blood pressure to less than 120 mm Hg versus less than 140 mm Hg in patients with high cardiovascular risk with and without diabetes or previous stroke: an open-label, blinded-outcome, randomised trial. Lancet. 2024;404:245-255. 38945140.