Annals of surgery
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To assess the demographics and characteristics of infections in surgical patients to define areas that deserve emphasis in surgical education. ⋯ Most infections treated by surgeons are hospital-acquired. Infections with gram-positive cocci and fungi are common, with pulmonary infections becoming more common. Fluoroquinolones have become important therapeutic agents. Depending on the type of practice, these data should be helpful to direct educational efforts so that surgeons can remain knowledgeable and active in the nonsurgical care of their patients.
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To determine whether the evolution of the authors' clinical pathway for the treatment of hemodynamically compromised patients with pelvic fractures was associated with improved patient outcome. ⋯ The evolution of a multidisciplinary clinical pathway, coordinating the resources of a level 1 trauma center and directed by joint decision making between trauma surgeons and orthopedic traumatologists, has resulted in improved patient survival. The primary benefits appear to be in reducing early deaths from exsanguination and late deaths from multiple organ failure.
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Comparative Study
Analysis of surgical success in preventing recurrent acute exacerbations in chronic pancreatitis.
To determine whether surgical intervention prevents recurrent acute exacerbations in chronic pancreatitis (CP). ⋯ Surgical intervention prevents recurrent acute exacerbations. The overall frequency of events was reduced in nearly all patients. Therefore, surgical intervention is indicated in patients with CP whose disease is characterized by recurrent acute exacerbations.
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Randomized Controlled Trial Clinical Trial
Attenuation of posttraumatic muscle catabolism and osteopenia by long-term growth hormone therapy.
To determine whether the beneficial effects of growth hormone persist throughout the prolonged hypermetabolic and hypercatabolic response to severe burn. ⋯ Low-dose recombinant human growth hormone successfully abates muscle catabolism and osteopenia induced by severe burn.
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Randomized Controlled Trial Comparative Study Clinical Trial
A prospective comparison of simultaneous kidney-pancreas transplantation with systemic-enteric versus portal-enteric drainage.
To compare pancreas transplantation with systemic-enteric (SE) versus portal-enteric (PE) drainage in a prospective fashion. ⋯ These results suggest that simultaneous kidney and pancreas transplantation with SE or PE drainage can be performed with comparable short-term outcomes.