Annals of surgery
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Multicenter Study
The Impact of Ineffective Esophageal Motility On Patients Undergoing Magnetic Sphincter Augmentation.
To evaluate and characterize outcomes of MSA in patients with IEM. ⋯ Patients with IEM undergoing MSA demonstrate improved quality of life and reduction in acid exposure. Key differences in IEM patients include lower rates of objective GERD resolution, lower resolution of existing dysphagia, higher rates of new onset dysphagia and need for dilation. GERD patients with IEM should be counselled about these possibilities.
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Randomized Controlled Trial
Professional Coaching and Surgeon Well-Being. A Randomized Controlled Trial.
To determine if individualized professional coaching reduces burnout, improves quality of life, and increases resilience among surgeons. ⋯ Professional coaching over 6 months improved burnout and resilience among surgeons, with reductions in improvement over the ensuing 6 months.
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Randomized Controlled Trial Multicenter Study
Cost-Effectiveness of Early Surgery Versus Endoscopy-First Approach for Painful Chronic Pancreatitis in the ESCAPE Trial.
Economic evaluation of early surgery compared to the endoscopy-first approach in CP. ⋯ In patients with painful CP and a dilated main pancreatic duct, early surgery was more cost-effective than the endoscopy-first approach.
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To define the relationship between the duration of smoking cessation and postoperative complications for patients with lung cancer undergoing surgical treatment. ⋯ Smoking cessation at least 3 weeks prior to the surgical treatment of lung cancer is associated with reduced morbidity and mortality. Providers should aggressively encourage smoking cessation in the preoperative period, since it can disproportionately impact outcomes in early-stage lung cancer.
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Randomized Controlled Trial
Neoadjuvant Chemotherapy with CAPOX versus Chemoradiation for Locally Advanced Rectal Cancer with Uninvolved Mesorectal Fascia (CONVERT): Initial Results of a Phase III Trial.
To compare neoadjuvant chemotherapy (nCT) with CAPOX alone versus neoadjuvant chemoradiotherapy (nCRT) with capecitabine in locally advanced rectal cancer (LARC) with uninvolved mesorectal fascia (MRF). ⋯ nCT achieved similar pCR and downstaging rates with lower incidence of perioperative distant metastasis and preventive ileostomy compared with nCRT. CAPOX could be an effective alternative to neoadjuvant therapy in LARC with uninvolved MRF. Long-term follow-up is needed to confirm these results.