Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Oct 2017
ReviewReview Typology: The Basic Types of Reviews for Synthesizing Evidence for the Purpose of Knowledge Translation.
With advances in medical practice and fields of research, reviews occupy a key position for summarizing existing knowledge. Due to the differences and overlap in terminology, the full potential for reviews may be lost due to confusion of indistinct approaches. The main objective of this study was to provide a descriptive outline of each of the common review types with their characteristics and examples in a health care system. ⋯ Nine common types of reviews and associated methodologies were evaluated against the already established SALSA framework. Their description, strengths and weaknesses are presented. The results provided a basic idea of different types of reviews based on the intended level of knowledge synthesis by which researchers can identify the appropriate type of review based on their intended audience.
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J Coll Physicians Surg Pak · Oct 2017
Case ReportsLate Presentation of Aggressive Fibromatosis Involving Head, Neck and Chest Wall.
Fibromatosis is a rare, benign, slow-growing and locally infiltrative tumour, caused by uncontrolled proliferation of fibrous tissue arising from muscles, connective tissue, fasciae and aponeurosis. It is also called desmoid tumour, which is very rare pathology representing only 0.03% of all neoplasms in human and around 3% of all soft tissue tumours. It is locally aggressive and usually invades the surrounding structures and has a high recurrence rate, even after surgical complete resection, which should be the first line of treatment. Here, we report a very rare case of extensive and disabling fibromatosis tumour in a 38-year male, involving three compartments of the right side of the head, neck and chest wall, which was completely excised surgically and had excellent postoperative results with no morbidity.
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J Coll Physicians Surg Pak · Oct 2017
Polymorphisms in the Growth Differentiation Factor 5 (GDF 5) Gene in Knee Osteoarthritis.
To identify the frequency of the rs143383 SNPin the GDF5 gene, which is located in the 5'-untranslated region of Turkish population with knee osteoarthritis (OA). ⋯ This study demonstrated that there is a correlation of +104T/C polymorphism in the 5'-UTR of GDF5 with knee OAin a Turkish population.