Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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The postpericardiotomy syndrome (PPS) is an important cause of morbidity and mortality following heart operation. This systematic review reviewed the literature regarding PPS. It was found to occur on day 18.3 ±15.9 after cardiac operations, most often after coronary artery bypass grafting, and mitral valve replacement. ⋯ Surgical trauma and cardiopulmonary bypass trigger the systemic inflammatory response, which results in antiheart autoantigen release, and the deposited immune complex could be found in the pericardial, pleural, and lung tissues, thereby provoking the occurrence of PPS. Therapeutic options for the refractory cases are long-term oral corticoids or pericardiectomy. Surgical intervention was warranted in 2.6% of the cases due to cardiac tamponade.
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Renal cell carcinoma (RCC) represents 2-3% of all cancers. Although RCC is rare, it is the most common urologic malignancy reported in pregnancy. Modality and timing of treatment during pregnancy represent a dilemma. ⋯ The patient was discharged on the third day, uneventfully. Histopathological examination revealed stage 1b clear-cell renal carcinoma, Furhman grade 2 with maximum diameter of 5 cm, no invasion of capsule, negative margine and without necrosis. Open techniques are better in pregnant patients with renal tumors because of short surgical and ischemia time and minimal bleeding.
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J Coll Physicians Surg Pak · Jan 2020
Multicenter Study Comparative StudySalivary Biomarker Interleukin-8 Levels in Naswar Users and Non-users.
Salivary biomarkers can be used as diagnostic and predictive aids in early detection of oral cancer or potentially malignant disorders. A cross-sectional comparative study was conducted over a period of one year from August 2016 to August 2017 in a multicentre setting in Islamabad. A total of 60 patients were recruited and divided into two equal groups of naswar users and non-users. ⋯ The results were then analysed by using independent t-test. Statistically significant difference was found regarding the levels of salivary IL-8 between the naswar users and non-users (p <0.001). The levels of salivary IL-8 in non-users were 33.39 ±22.44 pg/ml, while the increased levels of salivary IL-8 in naswar users were found to be 173.48 ±46.52 pg/ml.
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J Coll Physicians Surg Pak · Jan 2020
Can Urodynamic Findings of Overactive Bladder Determine the Treatment Effect of Urotherapy in Children?
To assess the correlation between urodynamic study findings and urotherapy treatment response in children with urotherapy-resistant overactive bladder (OAB). ⋯ Urodynamic verification of DO is not a prerequisite for urotherapy treatment response. Decreased cystometry bladder capacity (DCBC) found in UDS may suggest a poorer treatment response to urotherapy than patients with normal CBC.
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J Coll Physicians Surg Pak · Jan 2020
Comparative StudyOutcomes of Total Parathyroidectomy with Autotransplantation versus Subtotal Parathyroidectomy Techniques for Secondary Hyperparathyroidism in Chronic Renal Failure.
To compare the safety and the effectiveness of total parathyroidectomy with autotransplantation versus subtotal parathyroidectomy for refractory secondary hyperparathyroidism in patients with chronic kidney disease. ⋯ Both surgical options can be safely utilised in the management of refarctory secondary hyperparathyroidism. Moreover, regardless of the procedure used, all the parathyroid glands must be explored. However, due to high morbidity and failure rates of subsequent surgeries, the surgeon should be keen and thorough in the initial procedure.