Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Oct 2020
ReviewChloroquine and Hydroxychloroquine in COVID-19: Practice Implications for Healthcare Professionals.
Chloroquine (CQ) and its derivatives such as hydroxychloroquine (HCQ) remain mainstay of therapy for malaria. These drugs are also approved for certain autoimmune diseases including systemic lupus erythematosus. The antiviral activities of these drugs and their mechanisms have been studied in vitro previously against various viruses including severe acute respiratory syndrome coronavirus (SARS-CoV). ⋯ The authors used the keywords to find the relevant studies, like COVID-19, SARS-CoV-2, pandemic, complications, repositioning, toxicity, overdose, treatment plan, implication strategies, prevention, chloroquine, hydroxychloroquine, clinical trials, drug interactions, and practices advice, etc., in Pubmed and Google Scholar. This review aims to provide a detailed insight of practice implications related to these drugs, which would aid healthcare professionals to ensure the safe use of these drugs during the management of patients with COVID-19 disease. Key Words: Chloroquine, Hydroxychloroquine, COVID-19, SARS-CoV-2, Practice implications.
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J Coll Physicians Surg Pak · Oct 2020
ReviewPreparing for a Pandemic: Our Plans and Lessons Learnt as a Department in a Tertiary Care Hospital.
This is a descriptive article aiming to present and analyse the steps of preparedness and troubleshooting of problems faced at operating rooms and intensive care unit during the ongoing coronavirus infectious disease 2019 (COVID-19) pandemic in Our Lady of Lourdes Hospital, a tertiary care hospital in Ireland from February 2020 to March 2020. Concerning preparation, we reviewed all aspects of our clinical and potential logistic issues and their accessible solutions in times of limited resources. ⋯ We found good communication and training as critical factors in the preparation for a pandemic. Key Words: COVID-19, Pandemic, Preparation, Challenges.
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J Coll Physicians Surg Pak · Oct 2020
Letter Case ReportsA Diagnostic Challenge in COVID-19 Pandemic: PCP or COVID-19.