Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Oct 2020
Observational StudySpectrum of Addison's Disease in Children.
To determine the clinical presentation of Addison's disease in order to increase the awareness of presentation in Pakistani children. ⋯ There were 36 boys and 27 girls with a mean age at diagnosis of 3.92 and 4.96 years, respectively. Twelve patients were presented with an adrenal crisis following an acute illness. All of them had hyponatraemia; however, 10 had a hyperkalaemia and 8 had been reported with hypoglycaemia. Increased skin pigmentation was observed in 45 children with other identifiable features including weight loss, lethargy, and poor response in activities. Moreover 15 of them were identified with associated disorder (autoimmune polyendocrinopattay syndrome (APS), Allgrove or triple A syndrome, and adrenoleukodystrophy). Conclusion: Typical and atypical presentations of Addison's disease in children of Pakistani population are defined in this study which may assist in better management of Addison's patients. Key Words: Adrenal crisis, Hyponatremia, Hyperkalemia, APS, Allgrove, Adrenoleukodystrophy.
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J Coll Physicians Surg Pak · Oct 2020
Observational StudyAnatomical Variations of the Cystic Duct in Turkish Population and their Association with Biliary Track Stone.
To evaluate the anatomy and various anatomical variations of the cystic duct and their association with the stones in the biliary tract in the Turkish population. ⋯ Preoperative information of anatomical variations of the cystic duct is not only important for operative planning; but some variations are significantly associated with the cholelithiasis and/or choledocholithiasis. Key Words: Cystic duct, Variations, Bile stones, Cholelithiasis, Choledocholithiasis.
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J Coll Physicians Surg Pak · Oct 2020
Observational StudyDiagnostic Value of sCD163 Combined with PCT and HS-CRP in Patients with Gynecological Malignant Tumors and Fever.
To explore diagnostic values of sCD163 with PCT and HS-CRP in diagnosing infection among patients with gynecological malignant tumors and fever. ⋯ Combined detection of sCD163 with PCT and HS-CRP has a high diagnostic efficiency for early infection in patients with gynecological malignant tumors and fever, which is better than that of sCD163, PCT or HS-CRP alone. It can be used as an effective auxiliary examination method and an indicator for differential diagnosis. Key Words: sCD163, PCT, HS-CRP; Gynecology, Tumor, Infection, Diagnosis.
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J Coll Physicians Surg Pak · Oct 2020
Case ReportsMyxoid Liposarcoma with Cartilagenous Differentiation.
Myxoid liposarcoma (MLPS) is an adipocytic tumour and second commonest among the types of liposarcoma. It exhibits a wide histological spectrum. It is important to be aware of this diversity of morphology in this tumour to prevent a wrong diagnosis. ⋯ Patient was examined by oncologists. Wide local excision is in plan as two margins were involved by the tumour, while rest of the margins were very close to tumour. Key Words: Liposarcoma, Myxoid, Cartilaginous differentiation.
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J Coll Physicians Surg Pak · Oct 2020
Observational StudyThe Prognostic Effect of Metastatic Lymph Node Ratio in Operated Gastric Cancer Patients.
To assess the prognostic importance of metastatic lymph node ratio (MLNR) in operated gastric cancer patients. ⋯ The study contributed to the literature that MLNR is practical and useful as an independent prognostic factor predicting survival even better than tumor/node/metastasis (TNM) staging system. Key Words: Gastric cancer, Metastatic lymph node ratio, Prognostic factor, Surgery.