Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Dec 2021
Therapeutic Efficacy of Erythropoietin Alpha and Erythropoietin Beta in Anemia of Chronic Kidney Disease.
To compare the effectiveness of erythropoietin alpha and erythropoietin beta in anemia management in the hemodialysis population. ⋯ Erythropoietin alpha and erythropoietin beta have similar therapeutic efficacy in anemia management in chronic kidney disease patients. Reduced dosage of erythropoietin beta achieves and maintains the target hemoglobin level. Key Words: Efficacy, Erythropoietin, Anemia, Chronic kidney disease.
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J Coll Physicians Surg Pak · Dec 2021
Meta AnalysisThe Efficacy of Bronchoscopy versus Computerised Tomography in Initial Identification of Patients with Hemoptysis.
The effects of bronchoscopy and chest CT on early evaluation of patients with hemoptysis are still controversial. PubMed, EMBASE, and the Cochrane Library databases were systematically searched. Odds ratio (OR) was applied to assess the utility of bronchoscopy for hemoptysis etiology and site in comparison with CT in the various clinical processes. ⋯ In the cases of massive hemoptysis, bronchoscopy and CT had no statistical significance for identifying bleeding (OR=0.27, 95% CI: [0.02, 3.18]). The study suggested that bronchoscopy did not show superior diagnostic accuracy than CT for patients with hemoptysis at the first visit. Key Words: Hemoptysis, Bronchoscopy, CT, Meta-analysis.
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J Coll Physicians Surg Pak · Dec 2021
Randomized Controlled TrialEffects of S-adenosyl-L-Methionine Combined with Ursodesoxycholic Acid on Serum Endotoxin, MMP-9 and IL-18 in Neonates with Cholestasis.
To compare the effect of ursodesoxycholic acid (UDCA) with S-adenosyl-L-methionine (SAMe) plus UDCA in handling of cholestasis in neonates, and their influences on serum endotoxin, matrix metalloproteinase-9 (MMP-9) and interleukin 18 (IL-18). ⋯ Compared with UDCA alone, SAMe plus UDCA can more effectively improve the curative effect of neonatal cholestasis, and reduce serum endotoxin, MMP-9 and IL-18 levels. Key Words: Ursodesoxycholic acid (UDCA), Neonates, Cholestasis, Endotoxin, Matrix metalloproteinase-9 (MMP-9), Interleukin 18 (IL-18).
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J Coll Physicians Surg Pak · Dec 2021
Importance of Multifidus Muscle Activity as a Treatment Outcome Measure in Chronic Low Back Pain.
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J Coll Physicians Surg Pak · Dec 2021
Efficacy of Tranexamic Acid on Blood Loss in Thoracolumbar Spinal Fusion Surgery.
To investigate the effectiveness of topical tranexamic acid (TXA) use on bleeding and drain withdrawal time in adult patients undergoing thoracolumbar fusion surgery. ⋯ The topical use of TXA in spinal fusion surgery reduced perioperative blood loss. Key Words: Blood loss, Thoracolumbar spinal surgery, Tranexamic acid.