Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Aug 2021
Randomized Controlled TrialDexketoprofen vs. Tamsulosin vs. Silodosin vs. Tadalafil as Medical Expulsive Therapy for Distal Ureteral Stones in Men.
To assess the effectiveness of the use of dexketoprofen, tamsulosin, silodosin, and tadalafil in medical expulsive therapy for distal ureteral stones in male patients. ⋯ Tamsulosin, silodosin and tadalafil exhibited higher expulsion rates for distal ureteral stones in male patients, although none was significantly superior to the others. All three are safe, efficacious, and well-tolerated, with only very minor side-effects. Key Words: Dexketoprofen, Distal ureteral stones, Medical expulsive therapy, Silodosin, Tadalafil, Tamsulosin.
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J Coll Physicians Surg Pak · Aug 2021
Meta AnalysisVitrectomy alone or Vitrectomy Combined with Scleral Buckle in the Management of Giant Retinal Tears.
The aim of this study was to compare as to which treatment achieves better outcomes in the management of giant retinal tears (GRTs) - pars plana vitrectomy (PPV) alone or combined with scleral buckle (SB)? The Web of Science, PubMed, and Cochrane Library databases were searched from January 1, 1950 to October 1, 2020. Pooled odds ratios (ORs), 95% confidence intervals (CIs), heterogeneity, and publication bias were determined with Review Manager software. ⋯ According to the final anatomical success, final visual acuity, and risk factors of GRT ≥180°, there were no significant differences between PPV combined with SB and PPV alone for the management of GRT in the current study, except in decreasing the risk of RRD. Key Words: Giant retinal tear, Pars plana vitrectomy, Scleral buckling, Recurrent retinal detachment.
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J Coll Physicians Surg Pak · Aug 2021
Randomized Controlled TrialEffects of General Anesthesia Combined with Epidural Anesthesia on Cognitive Dysfunction and Inflammatory Markers of Patients after Surgery for Esophageal Cancer: A Randomised Controlled Trial.
To evaluate the impact of general anesthesia (GA) combined with epidural anesthesia (GAEA) on postoperative cognitive dysfunction (POCD) and inflammatory markers in patients with esophageal cancer (EC). Study Design: A randomised controlled trial. ⋯ Combining general and epidural anesthesia may reduce the incidence of POCD in patients undergoing esophagectomy by suppressing inflammatory response. Key Words: General anesthesia, Epidural anesthesia, Esophageal cancer, Postoperative cognitive dysfunction, Inflammatory markers.
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J Coll Physicians Surg Pak · Aug 2021
Treatment of Renal Colic by Nerve Blockade with Lidocaine Versus Intravenous Dexketoprofen.
To compare non-steroidal anti-inflammatory drugs (NSAIDs) with spinal nerve blockade of related dermatomes using lidocaine for pain palliation of patients admitted to the Emergency Department (ED) with an episode of renal colic. ⋯ Spinal nerve blocks with 2% lidocaine resulted in greater short-term pain relief than intravenous dexketoprofen in ED patients with renal colic. Key Words: Renal colic, NSAID, lidocaine, Nerve blockade.
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J Coll Physicians Surg Pak · Aug 2021
Computed Tomography-based Morphological Differences between Histologic Subtypes of Periampullary Ductal Adenocarcinoma.
To evaluate the computed tomography (CT)-based differences between pancreaticobiliary (PBST) and intestinal (IST) subtypes of periampullary pancreatic ductal adenocarcinomas (PDAC). ⋯ Infiltrative appearance is associated with PBST; whereas, nodular appearance more likely predicts IST. The potential role of CT lesion morphology on guiding appropriate chemotherapy in cases with no chance for surgery or biopsy requires addressing. Key Words: Intestinal differentiation, Pancreatobiliary differentiation, Periampullary adenocarcinoma.