Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Dec 2022
Randomized Controlled TrialOutcomes Associated with Indwelling Momentary Probe for Congenital Nasolacrimal Duct Obstruction Treatment.
To compare the outcomes of congenital nasolacrimal duct obstruction (CNLDO) patients undergoing nasolacrimal duct obstruction (NLD) probing in whom momentary probe indwelling was and was not performed. ⋯ Congenital nasolacrimal duct obstruction, Nasolacrimal duct probing, Indwelling time.
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J Coll Physicians Surg Pak · Dec 2022
Relationship of Gamma-glutamyl Transferase Levels at Diagnosis with Clinicopathological Features in idiopathic IgA Nephropathy.
To compare clinicopathologic features of idiopathic IgA nephropathy in terms of serum gamma-glutamyl transferase (GGT) levels. ⋯ Gamma-glutamyl transferase, IgA nephropathy, Proteinuria, Serum albumin, Mesangial Cellularity, Segmental glomerulosclerosis, Tubular atrophy.
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J Coll Physicians Surg Pak · Dec 2022
Case ReportsLocally Aggressive Mixed Epithelial and Stromal Tumour of Kidney Leading to Nephron Loss.
Mixed epithelial and stromal tumour (MEST) is a rare benign renal tumour. It is mainly found in perimenopausal women. We present a case of a 42-year female with no known comorbid who was presented in the outpatient clinic for the right flank pain. ⋯ Histopathology of the specimen revealed MEST. We demonstrate that MEST of the kidney may have an aggressive local behaviour leading to nephron loss. Key Words: Mixed epithelial and stromal tumour, Kidney, Benign, Renal neoplasm.
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J Coll Physicians Surg Pak · Dec 2022
Case ReportsStem Cell Transplantation in Glanzmann's Thrombasthenia: A Report of Two Adult Patients.
Glanzmann's thrombasthenia (GT) is an autosomal recessive bleeding disorder characterised by mucocutaneous bleeding. At molecular level, defect in platelet receptor glycoprotein (GP) IIb/IIIa leads to defective platelet aggregation. Anti-fibrinolytic agents, platelet transfusions, and factor rVIIa are used for prophylaxis before invasive procedures and treatment of bleeding events. ⋯ Both showed marked improvement in quality of life. To conclude, stem cell transplant is a viable treatment option for severe, difficult-to-control cases of GT. Key Words: Platelet disorders, Hematopoietic stem cell transplantation, Thrombasthenia.
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J Coll Physicians Surg Pak · Dec 2022
Case ReportsTreatment of Severe Congenital Scoliosis with Type ІI Respiratory Failure.
We report a case of a 14-year girl with severe congenital scoliosis (CS) and type ІІ respiratory failure (RF), who underwent preoperative halo-gravity traction in combination with intraoperative orthopaedic surgery on the spine based on the results of physical examination, pulmonary function tests (PFTs), computed tomography (CT), and blood gas analysis. The patient's coronal and sagittal Cobb's angles changed from 100° to 45° and 40°, respectively, and RF changed from type ІІ to type І after treatment. ⋯ During follow-up for nearly 3 years, no loss of deformity correction and no serious complications occurred, and the patient showed a good clinical outcome and balanced spine. Key Words: Congenital scoliosis, Halo-gravity traction, Respiratory failure.