Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Jan 2022
Relationship among Serum Homocysteine, Intercellular Adhesion Molecule-1, Monocyte Chemoattractant Protein-1, and Visual Impairment in Diabetic Macular Edema.
To determine the relationship among serum homocysteine (Hcy), intercellular adhesion molecule-1 (ICAM-1), monocyte chemoattractant protein-1 (MCP-1) and visual impairment in patients with diabetic macular edema (DME). ⋯ Levels of serum Hcy, ICAM-1 and MCP-1 in patients with DR complicated with DME were higher than those without visual disability; and levels of Hcy, ICAM-1 and MCP-1 in patients with visual disability were higher than those without visual disability. In patients with DR complicated with DME, increase of these serum markers may play an important role in visual disability. Key Words: Diabetic retinopathy (DR), Diabetic macular edema (DME), Hcy, ICAM-1, MCP-1, Visual impairment.
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J Coll Physicians Surg Pak · Jan 2022
Case ReportsRasmussen's Encephalitis: A Rare Cause of Intractable Seizures.
Rasmussen's encephalitis (RE) is a rare chronic progressive inflammatory disease of the brain that results in difficult-to-control seizures (mostly focal: epilepsia partialis continua), cognitive decline and progressive loss of neurological function including speech, motor skills with eventual paralysis of one half of the body (hemiparesis) and encephalitis. It is a disease that usually affects a single hemisphere and presents commonly at an early age. ⋯ We report a case consistent with the findings of RE in a 4.5-year male child, who presented with status epilepticus; and was diagnosed as a case of RE on clinical and radiological findings. Key Words: Rasmussen's encephalitis, Inflammatory disease, Seizures, Cognitive decline, Hemiparesis.
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J Coll Physicians Surg Pak · Jan 2022
EditorialD-dimer Testing in COVID-19: From Basics to Clinical Application.
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