Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Feb 2023
Randomized Controlled TrialClinical Efficacy of Early Administration of Human Immunoglobulin on Children with Severe Hand-foot-mouth Disease.
The objective of this study was to investigate the clinical effect of early administration of human immunoglobulin in children with severe hand, foot and mouth disease (HFMD) and its influence on serum c-reactive protein (CRP), creatine kinase (CK), and creatine kinase isoenzyme (CK-MB). One hundred and forty children with severe HFMD were randomly divided into Group A (n=70) and Group B (n=70) according to the random number table method. Group A was treated with routine treatment. ⋯ The total clinical effective rate of Group B was 92.9%, which was higher than that of Group A (80.0%, p=0.026). Early administration of human immunoglobulin may reduce the levels of serum markers CRP, CK, and CK-MB in children with severe HFMD. Key Words: Human immunoglobulin, Children, HFMD (Hand, foot and mouth disease).
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J Coll Physicians Surg Pak · Feb 2023
Chronic Pain and Health Related Quality of Life Assessment One Year After Total Knee Arthroplasty.
To assess chronic pain prevalence, health related quality of life (HRQOL), and factors associated with HRQOL in patients at least one year after total knee arthrosplasty (TKA). ⋯ Arthroplasty, Replacement, Knee, Pain, postoperative, Chronic pain, Neuralgia, Quality of Life.
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J Coll Physicians Surg Pak · Feb 2023
Hyperthermic Intraperitoneal Chemotherapy for Recurrent Nephroblastoma in Children.
For children with recurrent nephroblastoma, intraoperative HIPEC has little impact on the body, can significantly improve the effectiveness and reduce the recurrence rate, and does not increase the adverse reactions. ⋯ Randomised controlled trial.
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J Coll Physicians Surg Pak · Feb 2023
Observational StudyPeritumoural Oedema as a Predictor of Overall Survival for Patients with Posterior Fossa Metastases.
To analyse the relationship between peritumoural oedema volume and tumour volume in relation to the impact of metastatic posterior fossa tumour survival rates. ⋯ Cerebellar metastases, Cerebellum, OsiriX MD, Tumour volume.