Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
-
J Coll Physicians Surg Pak · Jun 2023
Clinicopathological and Survival Characteristics of Mismatch Repair Status and PD-1 Expression in Serous Ovarian Cancer.
To evaluate the clinicopathological characteristics of mismatch repair (MMR) deficiency and its clinical outcomes by performing immunohistochemistry (IHC) for MMR genes in the serous ovarian cancer (SOC) tumour sections. ⋯ Serous ovarian cancer, Microsatellite instability, Mismatch repair deficiency.
-
J Coll Physicians Surg Pak · Jun 2023
Observational StudyFactors Affecting the Efficacy of Regorafenib in Metastatic Colorectal Cancer: Is Tumour Sidedness Important?
To investigate the outcomes of regorafenib treatment in refractory metastatic colorectal cancer (mCRC) patients by primary tumour sidedness, the effects of previously targeted therapies, RAS status and inflammatory markers. ⋯ Colorectal cancer, Regorafenib, Tumour sidedness.
-
J Coll Physicians Surg Pak · Jun 2023
Comparison of Changes in Speciality Choices and Future Career Plans between Public and Private Medical Students Over Five Years of Medical Studies.
This study aimed to compare medical students' satisfaction with their choice of the medical field in their fifth year to their first year of MBBS and to compare speciality choices and career plans between public and private medical students. It was an online survey conducted from December 2020 to April 2021. Two consecutive classes of final-year medical students from five medical schools (2 public and 3 private) were included. ⋯ Of 468 responses (34.41% response rate), 331 (70.7%) were females. There was a significant change (p = 0.002) in the intention of students to practice abroad, however, no significant change (p=0.11) in their satisfaction with the medical profession was observed. Key Words: Career choices, Medical students, Medical schools, Personal satisfaction, Pakistan.
-
J Coll Physicians Surg Pak · Jun 2023
Observational StudySystemic Inflammatory Markers Predicting the Overall Survival of Patients Using Tyrosine Kinase Inhibitors in the First-line Treatment of Metastatic Renal Cell Carcinoma.
To identify prognostic inflammatory markers in metastatic renal cell carcinoma (mRCC) patients who received anti-vascular endothelial growth factor receptor (VEGFR) agents. ⋯ Sunitinib, Pazopanib, Renal cell carcinoma, Prognostic marker, Overall survival, Inflammatory.
-
J Coll Physicians Surg Pak · Jun 2023
Frequency of Premenstrual Dysphoric Disorder (PMDD) and Comparison of Quality of Life between Female Medical Students with and without Premenstrual Dysphoric Disorder.
To determine the frequency of Premenstrual Dysphoric Disorder (PMDD) in female medical students, and to compare the quality of life between those with and without PMDD. ⋯ WHOQOL-BREF, Premenstrual dysphoric disorder, Female medical students.