Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Nov 2024
Effect of Tissue Fragments Remain in the Karman Cannula on the Histopathological Diagnosis of Abnormal Uterine Bleeding.
The aim of this study was to perform histopathological analysis of residual material in the cannula by endometrial sampling using a Carmen injector, and to compare the results. The study was conducted in the Department of Gynaecology, Mardin Training and Research Hospital, Artuklu/Mardin, Turkiye, from December 2021 to June 2022. The study group consisted of 104 patients who presented to the outpatient clinic with complaints of abnormal uterine bleeding. ⋯ In Group 1, 16.7% of the patients were over-diagnosed, while 7.7% of the patients were over-diagnosed in Group 2. It would be beneficial to carefully remove the material remaining in the cannula and send it for pathological examination as it may affect the histopathological results. Key Words: Abnormal uterine bleeding, Probe curettage, Karman cannula, Histopathological evaluation.
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J Coll Physicians Surg Pak · Nov 2024
Case ReportsDetection of Hyperdiploidy from Cerebrospinal Fluid in B-Cell Acute Lymphoblastic Leukaemia.
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J Coll Physicians Surg Pak · Nov 2024
Observational StudyThe Efficacy and Safety of Trastuzumab in the Metastatic Breast Cancer.
The aim of this study was to explore the efficacy and safety of Trastuzumab-Deruxtecan (T-DXd) in metastatic breast cancer (mBC). This retrospective observational study was conducted between January 2021 and 2023. Patients' clinical and pathological characteristics and previous medicinal treatments were reviewed. ⋯ Some patients experienced gastritis, abnormal liver function, and weight gain, but none of the patients developed interstitial pneumonia. T-DXd can achieve significant and durable survival benefits with controllable safety in patients with HER2-positive or HER2 low-expressing mBC. Key Words: Metastatic breast cancer, Trastuzumab-Deruxtecan, Efficacy, Safety.
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J Coll Physicians Surg Pak · Nov 2024
Association of Vitamin D with Haematological Inflammatory Indices in Patients with Back Pain.
To assess the relationship between vitamin D and haematological inflammatory indices (HII) in chronic low back pain (CLBP) patients. ⋯ Inflammation, Low back pain, Neutrophil, Complete blood count, Vitamin D.