Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Apr 2024
Observational StudyCorrelation Between the Clinicopathological Features of Papillary Thyroid Carcinoma Complicated with Hashimoto's Thyroiditis, BRAF V600E Gene Mutation, and RET Gene Rearrangement.
To analyse the expression of BRAF V600E protein and RET gene rearrangement in papillary thyroid carcinoma (PTC) combined with Hashimoto's thyroiditis (HT) and to explore its clinical and pathological significance. ⋯ Papillary thyroid carcinoma, Hashimoto's thyroiditis, BRAF V600E protein, RET gene rearrangement.
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J Coll Physicians Surg Pak · Apr 2024
Acute Graft versus Host Disease in Beta Thalassemia Patients Following Allogeneic Haematopoietic Stem Cell Transplantation.
To analyse the frequency, risk factors, and clinical symptoms of acute graft-versus-host disease (aGvHD) in patients with beta-thalassemia major after allogeneic haematopoietic stem cell transplantation (HSCT). ⋯ Beta thalassemia major patients, Acute graft versus host disease, Allogeneic haematopoietic stem cell.
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J Coll Physicians Surg Pak · Apr 2024
Risk Factors and Risk Assessment for Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis.
To analyse the pertinent risk factors associated with post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP) and develop a predictive scoring system for assessing the risk of PEP in patients undergoing endoscopic retrograde cholangiopancreatography (ERCP) procedures. ⋯ Endoscopic retrograde cholangiopancreatography, Post-ERCP pancreatitis, Risk factors, Risk assessment, Preventive measure.
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J Coll Physicians Surg Pak · Apr 2024
Performance Evaluation of SARS-CoV-2 Rapid Antigen Test Among Symptomatic and Asymptomatic Patients in the Emergency Department of a Tertiary Care Hospital.
The aim of this study was to evaluate the diagnostic performance of the SARS-CoV-2 rapid antigen test (RAT) for the diagnosis of COVID-19 among symptomatic and asymptomatic patients. This retrospective study was done from 15th November 2021 to 15th December 2021, at National Medical Centre, Karachi, Pakistan. Two parallel nasopharyngeal swabs were collected from each patient, and SARS-CoV-2 RAT and SARS-CoV-2 real-time polymerase chain reaction (RT-PCR) were done. ⋯ High diagnostic accuracy of 91.81% and 96.29% were noted in symptomatic and asymptomatic patients, respectively. SARS-CoV-2 RAT (Roche) can be used for early diagnosis of SARS-CoV-2 patients in busy emergency departments. Key Words: COVID-19, Diagnosis, Rapid antigen test, RT-PCR, Emergency service.