Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Aug 2024
Complete Mesogastric Excision with D2 Lymphadenectomy for Gastric Cancer: Short-Term Results.
To compare the short-term results of complete mesogastric excision with the conventional surgical technique. ⋯ Complete mesogastrium excision, D2 lymphadenectomy, Gastric cancer, Gastrectomy, Mesogastrectomy.
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J Coll Physicians Surg Pak · Aug 2024
Observational StudyThe Consonance Between Medical Practitioners and Pharmacists Regarding Antimicrobial Stewardship Practices - An Observational Study.
To determine the consonance between medical practitioners and clinical pharmacists about antimicrobial resistance and stewardship in their practices. ⋯ Antimicrobial stewardship, Antimicrobial resistance, Anti-bacterial agents, Pharmacists.
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J Coll Physicians Surg Pak · Aug 2024
Outcomes of Mechanical Resection of Endometrial Polyps and Submucosal Fibroids Through TruClear™ Hysteroscopy.
To assess the efficacy of mechanical resection through TruClear™ hysteroscopy in patients with endometrial polyps and submucosal fibroids. ⋯ Fibroids, Hysteroscopy, Polyps, Endometrial resection, Menstrual bleeding.
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J Coll Physicians Surg Pak · Aug 2024
Meta AnalysisThe Impact of Nusinersen and Risdiplam on Motor Function for Spinal Muscular Atrophy Type 2 and 3: A Meta-Analysis.
Spinal muscular atrophy (SMA) is a prevalent paediatric neuromuscular disorder characterised by muscle weakness and atrophy resulting from degeneration of spinal cord anterior horn α motor neurons. Gene therapy formulations exhibit varying benefits and limitations, driving the need for patient-friendly treatment options tailored to specific populations. The objective of this meta-analysis was to assess the effectiveness of gene therapy for motor function in children with SMA. ⋯ Additionally, another study showed a moderate standardised effect size (Cohen's d) in favour of nusinersen concerning Hammersmith Infant Neurological Examination-Section 2 (HINE-2) (d = 0.48). However, it is important to note that further research with a longer duration of observation is required to strengthen the evidence. Key Words: Spinal muscular atrophy, Nusinersen, Risdiplam, Motor function, Cohen's d.
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J Coll Physicians Surg Pak · Aug 2024
Meta AnalysisTympanic Cavity Packing in Tympanoplasty Type 1: A Meta-Analysis.
Packing of tympanic cavity is generally considered an essential step in myringoplasty. However, each packing material comes with one or another side effect. The objective of this meta-analysis was to compare the results of Type 1 myringoplasty with or without packing. ⋯ Type 1 tympanoplasty performed with or without packing show comparable results in terms of graft uptake and functional success rate. However, if performed without packing, it takes shorter time, provides early hearing improvement and causes less aural fullness. Key Words: Tympanoplasty Type 1, Packing, Gelfoam, No-packing, Meta-analysis, Endoscopic myringoplasty.