Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Jun 2022
Antibiotic Disk Elution Method to Determine the Colistin Susceptibility against Enterobacterales and Non-fermenter Bacteria.
Colistin minimum inhibitory concentration among Enterobacterales and Non-fermenters was determined using the new susceptibility method, Colistin Broth Disk Elution Method (CBDE), and its sensitivity and specificity. This descriptive cross-sectional study was conducted at Pakistan Railway Hospital, Rawalpindi from October 2020 to August 2021. Gram-negative bacteria were isolated and identified using Gram Stain and standard biochemical profile. ⋯ The sensitivity and specificity of CBDE among Enterobacterales were 90.90% and 92.07% and for Pseudomonas aeruginosa 100% and 83.3% and for Acinetobacter baumannii 30% and 50% respectively. CBDE is simple, reliable, and cost effective to determine the colistin susceptibility among Enterobacterales and Pseudomonas aeruginosa while for Acinetobacter baumannii, this procedure is not useful. Key Words: Colistin susceptibility testing, CBDE, Enterobacterales, Non-fermenters.
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J Coll Physicians Surg Pak · Jun 2022
Observational StudyChanges in Serum Copeptin and Sphingosine 1-Phosphate in Patients with Restenosis after Stent Implantation of Symptomatic Intracranial Artery Stenosis.
To determine the changes of serum copeptin and sphingosine 1-phosphate (S1P) in patients with restenosis after stent implantation of symptomatic intracranial artery stenosis. ⋯ Copeptin, Sphingosine 1-phosphate (S1P), Symptomatic intracranial artery stenosis, Stent implantation, Restenosis.
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J Coll Physicians Surg Pak · Jun 2022
Impact of Urinary pH on the Efficacy of a Postoperative Single Instillation of Mitomycin-C.
To assess the effect of the urinary pH value on the efficacy of a postoperative single instillation of mitomycin-C. ⋯ Bladder cancer, Mitomycin-C, Single instillation, Urinary pH.
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J Coll Physicians Surg Pak · Jun 2022
Contribution of Metabolic Tumor Volume and Total Lesion Glycolysis to Predict Prognosis in Early-Stage Lung Cancer at Preoperative Staging.
To evaluate the effect of metabolic tumor volume (MTV) and total lesion glycolysis (TLG) values of the primary tumor measured by preoperative positron emission tomography/computed tomography (FDG-PET/CT) on survival in patients with operated non-small cell lung cancer (NSCLC). ⋯ Early-stage, Non-small cell lung cancer, MTV, TLG, NSCLC, Survival, FDG-PET/CT.
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J Coll Physicians Surg Pak · Jun 2022
Assessment of Pathological Complete Response in Patients with Breast Cancer Receiving Neoadjuvant Systemic Therapy.
To quantify the rate of pathological complete response (PCR) in a tertiary care hospital in Pakistan, and to explore the association of pathological complete response with tumour histology, tumour grade, and histological subtype based on receptors. ⋯ Breast cancer, Chemotherapy, Neoadjuvant systemic therapy, Pathological complete response, Surgery.