Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Nov 2021
Serum Hepcidin and Prohepcidin Levels in Nonfebrile and Febrile Neutropenia.
To compare the prohepcidin and hepcidin levels in the afebrile neutropenic period and neutropenic fever in patients with hematological malignancy. ⋯ Although there was no significant difference between afebnile neutropenia and neutropenic fever in patients in terms of hepcidin and prohepcidin levels, higher levels were found in both groups compared to the control group. Key Words: Hepcidin, Prohepcidin, Neutropenia, Febrile neutropenia.
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J Coll Physicians Surg Pak · Nov 2021
Observational StudyAssessing the Learning Process of Laparoscopic Sleeve Gastrectomy with Different Approaches.
To determine the learning curve (LC) of laparoscopic sleeve gastrectomy (LSG) based on an excess weight loss (EWL). ⋯ LSG can be safely performed even in centres that have just started bariatric/metabolic surgical operations. Although proficiency seems to require at least 40 cases, more than 80 operations are needed to complete the LC and achieve ideal results. Key Words: Bariatric surgery, Learning curve, Metabolic surgery, Laparoscopic sleeve gastrectomy (LSG).
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J Coll Physicians Surg Pak · Nov 2021
Insulin and Heparin Therapies in Acute Pancreatitis due to Hypertriglyceridemia.
To compare insulin infusion and heparin infusion, used to treat hypertriglyceridemia-induced acute pancreatitis in terms of efficacy. ⋯ The post-treatment third-day triglyceride levels of the insulin therapy group were statistically significantly lower compared to the heparin therapy group (432.5; 984, p<0.001, respectively). Conclusion: Insulin infusion, in addition to fluid therapy and electrolyte imbalance, was more effective than heparin therapy in patients with hypertriglyceridemia-induced acute pancreatitis. Key Words: Hypertriglyceridemia-induced acute pancreatitis, Insulin therapy, Heparin therapy.
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J Coll Physicians Surg Pak · Nov 2021
Inferior Vena Cava Collapsibility Index and Central Venous Pressure for Fluid Assessment in the Critically Ill Patient.
To determine the correlation of sonographic evaluation of inferior vena cava diameter and its collapsibility index with central venous pressure in both spontaneously breathing and mechanically ventilated patients in surgical ICU. Study Design: Cross-sectional study. ⋯ Total number of patients was 126. A significant correlation was seen between IVC measurements (inferior vena cava diameters and the collapsibility index) and CVP, (p<0.001), but the regression coefficients were less in patients who were mechanically ventilated (r=0.779 for IVC maximum diameter and -0.725 for collapsibility index) than the patients who were breathing spontaneously (r=0.850 for IVC maximum diameter and -0.899 for collapsibility index) Conclusion: Evaluation of IVC diameter and its collapsibility index is an easy and non-invasive method to evaluate intravascular volume status of critically ill patients. Its use is more helpful in patients who are spontaneously breathing than those who are mechanically ventilated. Key Words: Central venous pressure, Fluid status, Inferior vena cava diameter.
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A 21-year male presenting with left testicular mass and retroperitoneal lymphadenopathy underwent radical orchiectomy; and his pathological examination showed a mixed germ cell tumor composed of primitive neuroectodermal tumor mixed with mature teratoma. Six cycles of IE (ifosfamide, etoposide) and VAC (vincristine, doxorubicin, cyclophosphamide) chemotherapy were given after sperm preservation. ⋯ No tumor was detected in the removed lymph nodes, and all lymph nodes were reported as showing reactive changes. Key Words: Chemotherapy, Primitive neuroectodermal tumor, Surgery, Teratom, Testis.