Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Aug 2018
ReviewLow Prevalence of Colorectal Cancer in South Asians than White Population in UK: Probable Factors.
Colorectal cancer is common in White population in UK, while rare among South Asians living in UK. The main aim of this study was to find out probable reasons for very low prevalence of colorectal cancer among South Asians living in UK than White population. PubMed was searched by using key words and 2,153 articles were found and reviewed to find out related information. ⋯ Diet and lifestyle are important factors for low colorectal prevalence among South Asians in UK. Vegetable and fruit use, physical activity, alcohol abstention or low usage, less tobacco use, and fecal material time in large intestine are important factors for low colorectal cancer development. It was concluded that South Asians have very low colorectal cancer prevalence in the UK than White population, which may be related to their diet, dietary habit, and lifestyle.
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J Coll Physicians Surg Pak · Jul 2018
Epidemiology, Clinical Features and Consequences of Spinal Cord Injury in Children.
To describe epidemiology, clinical features and clinical consequences of Spinal Cord Injury (SCI) in children. ⋯ Majority of causes of SCI in children are similar to those reported in adult population. However, the commonest causes of SCI in children in Pakistan were firearm injury and bomb blast, which are rarely reported in other countries. Like adult population, these children with SCI are prone to developing pressure ulcer.
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J Coll Physicians Surg Pak · Jun 2018
Relation between Depressive Disorder and Iron Deficiency Anemia among Adults Reporting to a Secondary Healthcare Facility: A Hospital-Based Case Control Study.
To determine the relationship between iron deficiency anemia and depressive disorder; and identify the correlation between severity of anemia and depressive disorder. ⋯ This study concludes that there is relationship between iron deficiency anemia and depressive disorder; and severity of symptoms of DD increases with degree of IDA.
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J Coll Physicians Surg Pak · Jun 2018
Case ReportsLenalidomide Induced Toxic Epidermal Necrolysis and Del (5q): Co-occurrence of Rarities.
Primary myelofibrosis (PMF) is a clonal, BCR-ABL1 negative myeloproliferative neoplasm characterised by splenomegaly, leukoerythroblastic peripheral blood picture and bone marrow fibrosis. Different cytogentic abnormalities are documented in PMF which have impact on clinical outcome and overall survival. Del 5q31 is documented in only 0.8% of PMF patients and is associated with poor outcome and increased risk of progression to acute leukemia. ⋯ His cytogenetics showed del 5q positivity. He was started on lenalidomide but developed toxic epidermal necrolysis, resultantly lenalidomide was stopped. Skin eruptions are a known entity in patients with lenalidomide therapy; but to date, there is no reported case of lenalidomide induced toxic epidermal necrolysis (TEN) in patients with myelofibrosis.