Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
-
J Coll Physicians Surg Pak · Dec 2014
Comparative Study Observational StudyAxial length variability in cataract surgery.
To determine the mean axial length and biometric measures in patients undergoing cataract surgery and further compare the variability of axial length between the gender and with age. ⋯ The mean axial length of patients undergoing cataract surgery was 22.96 ± 1.04 mm, was comparable to Indian and Chinese population but shorter than the Western population. Females had shorter axial lengths, similar to other studies. Axial length was positively associated with age among the females, the cause of which is yet to be determined.
-
J Coll Physicians Surg Pak · Dec 2014
The ringing bells: perspective of Karachiites regarding noise pollution.
To identify the awareness regarding noise pollution and its adverse effects on human health in the people of urban areas of Karachi. ⋯ Awareness sessions need to be conducted for the public regarding the effects of noise pollution on health with formulation of laws and regulations.
-
To determine the clinico-pathological and histological features of Chondroblastoma (CB). ⋯ CB is a benign tumor but has potential for recurrence. Males are more affected, second decade is more common and distal femur is most common site. Metaphysis, clavicle, temporal bone and metacarpal were the rare sites of CB. Histological features predictive of recurrence were not separately identified.
-
J Coll Physicians Surg Pak · Nov 2014
Randomized Controlled TrialEfficacy of clarithromycin in pityriasis rosea.
To determine the efficacy of clarithromycin in the treatment of Pityriasis Rosea (PR). ⋯ Clarithromycin is not effective in treatment of pityriasis rosea.
-
J Coll Physicians Surg Pak · Nov 2014
Observational StudyPrognostic role of SIRT1 in hepatocellular carcinoma.
To determine the clinical significance of silent mating type information regulation 2 homolog 1 (SIRT1) expression in Hepatocellular Carcinoma (HCC) and its association with P53 and Yes-associated protein 2 (YAP2) expression. ⋯ SIRT1 was overexpressed in HCC and the expression was positively related to P53 and YAP2 expression. As the nuclear SIRT1 functions as a tumor promoter and cytoplasmic SIRT1 functions as a tumor suppressor, the role of SIRT1 in HCC should be reconsidered.