Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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A young man presented with recurrent episodes of mild jaundice. Apart from conjugated hyperbilirubinemia, other liver function tests were always normal. Clinical suspicion of Dubin-Johnson syndrome was raised. ⋯ Dubin-Johnson syndrome is a benign condition, which results from a hereditary defect in biliary secretion of bilirubin pigments, and manifests as recurrent jaundice with conjugated hyperbilirubinemia. The defect is due to the absence of the canalicular protein MRP2 located on chromosomes 10q 24, which is responsible for the transport of biliary glucuronides and related organic anions into bile. No treatment is necessary and patients have a normal life expectancy.
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A 60 years old male presented with a 10 years history of chronic discharging perineal sinuses with inguinal lymphadenopathy. Biopsy of the inguinal lymph node revealed follicular B-cell non-Hodgkin's lymphoma while the biopsy of the sinuses was non-specific. It was diagnosed as a case of primary nodal NHL with secondary cutaneous manifestations of multiple perineal sinuses (paraneoplastic dermatosis). After two courses of chemotherapy, the discharge from the sinuses disappeared and the lesions healed by scarring.
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J Coll Physicians Surg Pak · Aug 2007
Knowledge, attitude and practices (kap) regarding blood donation prevalent in medical and paramedical personnel.
To assess Knowledge, Attitude and Practices (KAP) regarding voluntary blood donation prevalent in medical and paramedical personnel having basic level of awareness on the subject. ⋯ It is concluded from our study that there is an urgent need to create and strengthen programs for motivation, recruitment and retention of Voluntary Non-remunerated blood Donors (VNDs) in our country on the basis of following observations of the study:- More blood donations from medical doctors are observed in our study as compared to the paramedics. This phenomenon seems to be related to the basic and advanced medical education of doctors that obviously tends to increase their level of awareness manifolds as compared to the paramedics. Maximum number of non-donors (both medical and paramedical) in the study stated the reason of their non-donation being "no one has ever asked them to donate blood". This implies that even the increased level of awareness on the subject does not result in actual act of donating blood. It would, therefore, not be justified to expect from general public 'humane gesture of preserving life' without creating in them awareness of the importance of voluntary blood donation.
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J Coll Physicians Surg Pak · May 2007
Dermatological disorders related to cultural practices in black Africans of Sierra Leone.
To describe various skin manifestations directly or indirectly related to the prevalent cultural practices in the local community of black Africans of Sierra Leone. ⋯ Prevalent cultural practices in black Africans do play a role in causation of various skin disorders. For a dermatologist, it becomes imperative to be cognizant of the signs and symptoms associated with these practices for proper diagnosis and appropriate treatment.
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J Coll Physicians Surg Pak · May 2007
Comparative StudyComparison of diagnostic accuracy of non-invasive tests for Helicobacter pylori infection in children.
To compare urea breath and stool antigen in children, with histological diagnosis for Helicobacter pylori (H.pylori) infection. ⋯ Both the noninvasive tests were found to be sensitive and specific as compared with histological identification, for the diagnosis of H. pylori in our pediatric population. The accuracy of urea breath test was better than the stool antigen test but later was easier to perform and could fulfill the criteria for a rapid bedside diagnostic test.