Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Nov 2024
Observational StudyIdentification and Validation of a Novel PANoptosis-related Gene Signatured for Osteosarcoma as Prognostic Model.
To construct and validate a prognostic model for osteosarcoma prognostication and therapeutic potential of PANoptosis- related genes. ⋯ PANoptosis-related genes, Osteosarcoma, Prognosis, Bioinformatics, Tumour micro-environment.
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J Coll Physicians Surg Pak · Nov 2024
Editorial LetterProstate Cancer Treatment cannot be Enhanced without including Comprehensive Cancer Rehabilitation.
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J Coll Physicians Surg Pak · Nov 2024
EditorialFrom Dissertation to Original Paper: A Journey Towards Quality and Standards in Research.
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J Coll Physicians Surg Pak · Nov 2024
Immunomodulatory Potential of Melatonin in Immunosuppression: An in-vivo Study.
To assess the immunomodulatory effects of melatonin on the acquired immunity of immunosuppressed male Wistar rats by checking Interleukin 6 (IL-6) levels, total leucocyte counts (TLC), and differential leucocyte counts. ⋯ Melatonin, Immunomodulation, Rats, Interleukin-6, Acquired immunity, Cyclophosphamide.
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J Coll Physicians Surg Pak · Oct 2024
Meta AnalysisEffects of Aerobic Exercise on Vascular Wall Thickness: A Meta-Analysis of Pre-Clinical Trials on Rat Model.
Exercise instigates adaptations in structural as well as functional organisation of the body at tissue and organ levels. However, the effect of exercise on vascular wall morphology is still under investigation. The objective of the review is to provide a meta-analysis of data from the previously published research to provide compiled analysis to determine the effect of exercise on the thickness of large-sized vessel walls. ⋯ However, an extensive review of the literature currently available on the topic has shown mixed findings that are consistent with the study and vice versa. Therefore, it indicated the need for sub-group analysis with different types of exercises for more peculiar clinical approaches. Key Words: Morphometry, Animal studies meta-analysis, Media thickness, Physical activity, Vascular morphology.