Journal of evaluation in clinical practice
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Routinely recorded coding data are increasingly being used for clinical research, but the quality of that data is often variable. The clinical coding of pleural empyema has not been studied. If data are not accurately recorded, linking coding data through, for example, Hospital Episode Statistic data (HES), will lead to inappropriate conclusions. ⋯ In the centres studied, empyema coding was generally good (>85% accuracy), although some cases were miscoded. Using codes for elective admissions helped to differentiate post-operative from community acquired empyema. It is likely empyema is under rather than over-recorded in HES data.
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Meta Analysis
Effects of eradicating Helicobacter pylori on metachronous gastric cancer prevention: A systematic review and meta-analysis.
Helicobacter pylori (H pylori) infection is closely associated with the incidence of gastric cancer. However, whether H pylori eradication prevents metachronous gastric cancer remains uncertain. The aim of our study is to assess how eradicating H pylori influences metachronous gastric cancer onset following treatment of early stage gastric cancer via endoscopic resective surgery. ⋯ Eradicating H pylori via therapeutic treatment can effectively reduce rates of metachronous gastric cancer, and as such, it should be implemented in H pylori-infected individuals recently treated for early stage gastric cancers via endoscopic resection.
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Laparoscopic sleeve gastrectomy (LSG) and laparoscopic Roux-en-Y gastric bypass (LRYGB) are widely performed to cure obesity and obesity-related diseases. Our aim was to compare these two procedures. ⋯ Both LSG and LRYGB can be performed with very low conversion to open rate and mortality rate. The readmission rate and re-operation rate are comparable between these two surgeries. The efficacy of these two surgeries on EWL and T2DM is equivalent, but LSG has an advantage over LRYGB in operation time and early complications rate.
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Current meta-analysis was conducted aiming to assess the efficacy and safety of recombinant human interleukin-11 (rhIL-11) in the treatment of acute leukaemia (AL) patients with chemotherapy-induced thrombocytopenia (CIT). ⋯ Our findings suggest that rhIL-11 is effective and safe in the treatment of CIT in patients with AL.
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The present study aimed to define thresholds for perioperative fluids and weight gain after urgent colectomies. ⋯ Fluid administration of 3 L at the day of surgery and weight gain of 2.3 kg at POD 2 may represent critical thresholds for adverse outcomes after urgent colectomy. The suggested thresholds need to be confirmed through independent validation.