Seminars in cutaneous medicine and surgery
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Semin Cutan Med Surg · Mar 2019
ReviewPharmacogenomics in dermatology: tools for understanding gene-drug associations.
Pharmacogenomics aims to associate human genetic variability with differences in drug phenotypes in order to tailor drug treatment to individual patients. The massive amount of genetic data generated from large cohorts of patients with variable drug phenotypes have led to advances in this field. ⋯ The implementation of clinical pharmacogenomics within health care systems remains an area of ongoing development. This review provides an introduction to the field of pharmacogenomics and to current pharmacogenomics resources using examples of gene-drug associations relevant to the field of dermatology.