Archivos argentinos de pediatría
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Arch Argent Pediatr · Feb 2020
Case Reports[Cutaneous hyperpigmentation secondary to vitamin B12 deficiency in an infant].
Cutaneous hyperpigmentation is a rare clinical feature of vitamin B12 (cobalamin) deficiency. The cause is unknown and there are different hypothesis about the pathogenesis of the hyperpigmentation. ⋯ Based on the clinical suspicion of vitamin B12 deficiency, we performed a laboratory dosage that showed decreased levels of cobalamin, reason for which replacement therapy was indicated. It highlights the importance of the presumption of vitamin B12 deficiency as a cause of cutaneous hyperpigmentation and its rapid resolution after the establishment of the appropriate treatment.