Clinical oral investigations
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Randomized Controlled Trial
Oral pregabalin for postoperative pain relief after third molar extraction: a randomized controlled clinical trial.
The aim of this randomized controlled clinical trial was to evaluate the efficacy and safety of pregabalin administered pre- and postoperatively in patients with pain and swelling due to the surgical removal of impacted lower third molars. ⋯ These findings suggest that pregabalin may be useful to control acute postoperative pain. Adverse effects are known to be reduced at the low pregabalin dose used in our study.