Clinical oral investigations
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This study assessed the frequency of nuclear morphological changes in gingival epithelial cells, as a biomarker for DNA damage, in individuals with periodontitis, before and after implementation of periodontal therapy, and compared the morphology to those with healthy periodontal tissues. ⋯ The micronucleus test could serve as a tool for estimating genotoxic damage in assessing the success of periodontal therapy.