British journal of anaesthesia
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Randomized Controlled Trial Comparative Study Clinical Trial
Effects of concentration of local anaesthetic drugs in extradural block.
An increase in the concentration of bupivacaine from 0.5% to 0.75% and etidocaine from 1.0% to 1.5% for extradural block resulted in a more rapid onset of sensory analgesia and motor blockade, a greater frequency of adequate analgesia,a greater depth of motor block and a longer duration of sensory analgesia and motor blockade. An increase in the concentration of prilocaine from 2% to 3% failed to reveal any significant advantage. The use of the more concentrated solutions of bupivacaine and etidocaine would appear to afford significant clinical advantages in extradural anaesthesia for surgery.
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A patient became wakeful during a general anaesthetic for Caesarean section. The isolated forearm technique for assessing wakefulness was in use. ⋯ After the operation she was able to remember the experience, being told about the delivery, and hearing her baby cry. The words from a tape-recording of the anaesthetist's postoperative visit on the next day are presented.