British journal of anaesthesia
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Review Meta Analysis
A Bayesian network meta-analysis on the effect of inodilatory agents on mortality.
Inodilators are commonly used in critically ill patients, but their effect on survival has not been properly studied to date. The objective of this work was to conduct a network meta-analysis on the effects of inodilators on survival in adult cardiac surgery patients, and to compare and rank drugs that have not been adequately compared in head-to-head trials. ⋯ Levosimendan seems to be the most efficacious inodilator to improve survival in cardiac surgery.
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Our aim was to review the recent evidence for the efficacy of peripheral regional anaesthesia. ⋯ The majority of peripheral regional anaesthetic techniques have been shown to produce benefits for patients and hospital efficiency. Further interventional trials are required to clarify such benefits for supraclavicular block and transversus abdominis plane block and to ascertain any longer-term benefits for almost all of the blocks reviewed. Permanent complications of peripheral regional anaesthetic blocks are rare but accurate estimates of their incidence are yet to be determined.
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Multicenter Study
Wrong-site nerve blocks: 10 yr experience in a large multihospital health-care system.
Although wrong-site surgery has garnered extensive scrutiny, the incidence of wrong-site blocks remains unknown. Our study thus sought to quantify the incidence of wrong-site blocks and examine some of their associated risk factors in our multihospital health-care system. ⋯ Our study provides the first incidence data on wrong-site block in a large patient population and can help hospitals to develop policies based on these data. It is yet to be determined whether active intervention can eliminate this adverse event.
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Multicenter Study
Risk scores to facilitate preoperative prediction of transfusion and large volume blood transfusion associated with adult cardiac surgery†.
The aim of this study was to develop two novel risk prediction scores for transfusion and bleeding that would be used to inform treatment decisions, quality assurance, and clinical trial design in cardiac surgery. ⋯ Two new risk scores for any RBC transfusion or LVBT among cardiac surgery patients have excellent discrimination, and could inform clinical decision making.