British journal of anaesthesia
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Review Meta Analysis
A Bayesian network meta-analysis on the effect of inodilatory agents on mortality.
Inodilators are commonly used in critically ill patients, but their effect on survival has not been properly studied to date. The objective of this work was to conduct a network meta-analysis on the effects of inodilators on survival in adult cardiac surgery patients, and to compare and rank drugs that have not been adequately compared in head-to-head trials. ⋯ Levosimendan seems to be the most efficacious inodilator to improve survival in cardiac surgery.
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Our aim was to review the recent evidence for the efficacy of peripheral regional anaesthesia. ⋯ The majority of peripheral regional anaesthetic techniques have been shown to produce benefits for patients and hospital efficiency. Further interventional trials are required to clarify such benefits for supraclavicular block and transversus abdominis plane block and to ascertain any longer-term benefits for almost all of the blocks reviewed. Permanent complications of peripheral regional anaesthetic blocks are rare but accurate estimates of their incidence are yet to be determined.