International journal of clinical practice
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Int. J. Clin. Pract. · May 2021
Personal protective equipment (PPE) guidance during a global pandemic: A statistical analysis of National perceived confidence, knowledge and educational deficits amongst UK-based doctors.
On the 11th of March 2020, the World Health Organisation (WHO) declared a global pandemic following the upsurge of the novel coronavirus disease 2019 (COVID-19). Unprecedented global demand for personal protective equipment (PPE) resulted in restricted availability, as well as evolving guidance on use, the latter of which was complicated by conflicting guidance provided by numerous healthcare bodies. ⋯ Ensuring uniformity in published guidance, coupled with education may aid knowledge and subsequent confidence regarding the appropriate use of PPE. The absence of a unified consensus and sustained training not only poses significant ramifications for patient and healthcare professional (HCP) safety, but also risks further depletion of already sparse resources. Because of the novelty of COVID-19, appropriate PPE is continually evolving leaving an absence in formal training and education. This paper reveals insight into confidence and knowledge of PPE amongst doctors of various specialities/grades during a global pandemic, highlighting key deficits in education and training.
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Int. J. Clin. Pract. · May 2021
Randomized Controlled TrialThe antioxidant and anti-inflammatory effects of astaxanthin supplementation on the expression of miR-146a and miR-126 in patients with type 2 diabetes mellitus: A randomized, double-blind, placebo-controlled clinical trial.
The pathogenesis of type 2 diabetes mellitus (T2DM) is associated with chronic oxidative stress and inflammation. It is well known that the expression of some miRNAs such as miRNA-146a is upregulated in diabetic and hyperglycaemic patients, whereas circulating miRNA-126 is reduced. Therefore, we aimed to determine the effects of astaxanthin (AST) supplementation on the circulating malondialdehyde (MDA) and interleukin 6 (IL-6) levels, and the expression of miR-146a and miR-126 in patients with T2DM. ⋯ AST supplementation might be beneficial for improving circulating MDA and IL-6 and the down-regulation of miR-146a. However, future investigations are suggested to confirm these results.
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Int. J. Clin. Pract. · May 2021
Multicenter StudyFactors Affecting Long Term Renal Functions after Partial versus Radical Nephrectomy for Clinical T1 Renal Masses: A Multicenter Study of the Urooncology Association, Turkey.
To compare the functional outcomes of patients who underwent partial (PN) or radical nephrectomy (RN) for clinical T1 (cT1) renal tumours using the Kidney Cancer Database of the Urooncology Association, Turkey. ⋯ For the treatment of stage T1 kidney tumours, open or laparoscopic partial nephrectomy has the benefit to preserve renal function.
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Int. J. Clin. Pract. · May 2021
Randomized Controlled TrialThe effect of Oxygen application with nCPAP for the prevention of desaturation during EBUS-TBNA.
EBUS-TBNA is a frequently used diagnostic method for mediastinal/hilar lymphadenopathies and masses. This procedure is performed with intravenous sedation (IVS). During IVS, patients often develop hypoxemia and nasal oxygen delivery is insufficient in some patients. The aim of this study was to investigate the effect of oxygen application with nCPAP on hypoxemia during EBUS-TBNA. ⋯ Oxygen application by nCPAP during EBUS-TBNA under IVS, significantly reduces desaturation time. Oxygen delivery with nCPAP seems to be a better choice especially for the patients with high Mallampati index.
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Int. J. Clin. Pract. · May 2021
Family medicine research assistants' experiences during COVID-19 pandemic: A qualitative study.
We aimed to learn about the experiences of family medicine research assistants during COVID-19 pandemic and to obtain information about improvement activities that can be done in similar situations. ⋯ Family medicine research assistants have important roles during pandemic. However, in this period, it is very important to know their views to provide the most accurate management and to meet their training needs.