International journal of clinical practice
-
Int. J. Clin. Pract. · May 2021
Review Case ReportsAtrial fibrillation and cardiac arrhythmia associated with acute dental infection: a systematic literature review and case report.
This paper outlines how oral diseases such as periodontitis and periapical periodontitis may be linked to cardiovascular disease, atrial fibrillation and cardiac arrhythmia. We undertake a systematic review of the literature focused on acute dental infection and types of cardiac arrhythmia and also describe an illustrative case where an acute dental infection diagnosed as periapical periodontitis was associated with the occurrence of atrial fibrillation. ⋯ Based on the biological plausibility of a link between acute dental infection and types of cardiac arrhythmia such as atrial fibrillation, together with the case report presented, it is evident that further study in this area is needed. If there are possible cardiovascular consequences for patients suffering from acute dental infection, then this will have implications for healthcare staff since they can integrate professional advice relating to oral health with cardiovascular disease and atrial fibrillation. Screening programmes situated in dental settings can facilitate early intervention and prevention producing benefits for patients and savings to the health system.
-
Int. J. Clin. Pract. · May 2021
Meta AnalysisDexmedetomidine versus fentanyl as adjuvants to ropivacaine for epidural anesthesia：a systematic review and meta-analysis.
Several randomized controlled trials (RCTs) have evaluated the use of dexmedetomidine versus fentanyl as adjuvants to ropivacaine for epidural anaesthesia, yet the results are conflicting. We aimed to conduct this meta-analysis to assess the effects and safety of dexmedetomidine and fentanyl as adjuvants to ropivacaine for epidural anaesthesia. ⋯ Dexmedetomidine is better than fentanyl as adjuvant to ropivacaine for epidural anaesthesia with better effects and less adverse events.
-
Int. J. Clin. Pract. · May 2021
Review Meta AnalysisComparison of the Effect of Educational and Self-Management Interventions on Adherence to Treatment in Hemodialysis Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Adherence to fluid intake, diet, and drug management is very important in hemodialysis patients. Educational and self-management interventions are frequently used to improve adherence to treatment in hemodialysis patients. ⋯ The analysis shows that educational and self-management interventions had a beneficial effect on adherence to fluid intake, diet, and drug management and no difference between these interventions. Therefore, these interventions can be used by healthcare professionals. It is also recommended that these interventions be well defined and transferable to routine clinical practice.
-
Int. J. Clin. Pract. · May 2021
Meta AnalysisEfficacy and Safety of Mirogabalin Treatment in Patients with Diabetic Peripheral Neuropathic Pain: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
We aimed to perform a systematic review and meta-analysis to examine the efficacy and safety of mirogabalin in patients with diabetic peripheral neuropathic pain (DPNP). ⋯ Our systematic review and meta-analysis revealed that in patients with DPNP, mirogabalin treatment was superior to placebo and pregabalin in decreasing the ADPS over time. Besides, mirogabalin was largely safe and associated with some adverse events that could be managed conservatively.